Caffeine’s Effect on Those With Hepatitis/Liver Disease

Caffeine is present in coffee, tea, chocolate, cola, and some over-the-counter medications. Caffeine is metabolized through the liver.  However, caffeine itself is not directly harmful to the liver. In fact, one study even suggested that coffee, but not other caffeine containing drinks, may delay progression of liver disease  to cirrhosis. (This result has not been substantiated by other studies). In moderation (one to two cups of a caffeine-containing beverage per day), caffeine may suppress the fatigue associated with liver disease to some extent. However, higher amounts of caffeine may cause irritability, restlessness, and insomnia. Some people may experience a rapid heartbeat and/or palpitations from caffeine consumption. Excessive intake of caffeine may put people with chronic liver disease at increased risk for osteoporosis and bone fractures. And, in people with cirrhosis, the metabolism of caffeine is slowed, resulting in higher concentrations of caffeine in the blood.  Thus, people with cirrhosis should limit their caffeine intake to one cup of coffee or tea per day.  In fact, it is best for all people with liver disease to consume caffeine in moderation. This is especially important for people taking interferon, as this medication may, by itself, cause symptoms similar to those caused by caffeine.

     Of interest, is that a recent study has suggested that caffeine may in fact be advantageous to people with liver disease.  However, further study will need to be conducted to prove this issue.

All contents of this article are Copyright © Melissa Palmer, MD

Melissa Palmer, MD is the author of " Dr. Melissa Palmer's Guide of Hepatitis and Liver Disease". (Published 2004. Penguin Putnam).

The office of Melissa Palmer, M.D. is located at:

1097 Old Country Road Suite 104

Plainview, N.Y 11803

To arrange an appointment with Dr. Palmer, call

(516) 939-2626

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